Complement-Mediated Thrombotic Microangiopathy (CM-TMA)—also known as atypical HUS sounds complicated and foreign to many, however all of us have probably seen it in our practice.  Corby Lust has become an expert in this compliment related subject and will make it easy to identify patients at risk including patients with cerrtain triggers: 

• Microangiopathic hemolytic anemia (MAHA): schistocytes, elevated LDH, low haptoglobin
• Thrombocytopenia
• Acute kidney injury (AKI) or rising creatinine

Consider 

• Autoimmune disease (e.g., SLE): ANA, dsDNA, complement levels
• Pregnancy/postpartum
• Transplantation
• Infections (e.g., COVID-19, influenza)
• Malignancy
• Medications (e.g., calcineurin inhibitors)

If TMA persists after treating the primary condition, CM-TMA should be strongly considered.

We will have a taco bar catered from Illegal Pete's and of course freshly brewed beer from Odell's!  Bring an NP, PA, or MD friend for $15 to help cover cost and be sure to let us know to order extra food beforehand :)

We are looking forward to seeing you there!  

NCNPC Board Members